At Classia Health, we believe many chronic diseases cannot be fully understood by looking at symptoms or individual organs alone. We look deeper—at the metabolic and molecular environment of the cell.
Our approach integrates metabolomics, metabolic health, gene regulation and cellular biology to understand the biological processes associated with disease and identify potentially modifiable drivers.
Many chronic diseases that appear to affect different organs can share disturbances in metabolism, cellular signalling, hormones, inflammation and energy regulation. At CIMH, we use metabolomics to look deeper at metabolites and metabolic pathways that can provide clues to ongoing biological activity.
By integrating metabolomics with clinical assessment, blood and urine biomarkers, nutrition, lifestyle and molecular biology, we investigate potentially modifiable metabolic drivers associated with conditions ranging from diabetes, hypertension, obesity, fatty liver, PCOS, thyroid and lipid disorders to complex diseases such as CKD and cancer.
DNA matters, but biological function is also shaped by metabolism, cellular signalling, gene regulation and the environment in which cells operate.
Genes can tell us about biological potential. Metabolites can provide information about ongoing biological activity. They are influenced by food and nutrition, gut microbiome, hormones, medicines, physical activity, sleep, environmental exposures, organ function and cellular metabolism.
By examining metabolic patterns alongside clinical information and conventional laboratory markers, we aim to develop a deeper understanding of a patient’s metabolic state.
DNA contains biological instructions. Gene expression determines which instructions are being used by cells. Metabolism provides substrates, energy and signalling molecules involved in cellular activity.
Explore each specialty below. Every section has its own clinical focus, biological framework and personalised approach.
Diabetes • Hypertension • Obesity • Fatty Liver • PCOS • Thyroid & Lipid Disorders
Explore Specialty →02Cancer Metabolism • Cancer Care • Prevention & Survivorship
Explore Specialty →03CKD • Diabetic Kidney Disease • Hypertensive Kidney Disease • Metabolic Risk Management
Explore Specialty →04Cellular Health • Regeneration • Mitochondrial Health • Healthy Ageing Research
Explore Specialty →05Biological Age • Cardiometabolic Health • Body Composition • Fitness • Healthy Ageing
Explore Specialty →06Metabolic Health • Frailty Prevention • Mobility • Nutrition • Assisted & Day Care
Explore Specialty →Different diseases affect different organs, but underneath them exists an interconnected biological network. Classia Health combines clinical medicine with metabolic and molecular science to understand these interactions, identify modifiable biological drivers and measure how the body responds to intervention.
Blood sugar, blood pressure, body weight, cholesterol and liver enzymes are important measurements—but they do not tell the whole biological story.
At Classia Health, we investigate the metabolic environment behind these abnormalities.
Food, physical activity, sleep, stress, hormones, medicines and environmental exposures can influence glucose metabolism, insulin signalling, lipid metabolism, inflammation, mitochondrial function and cellular signalling.
Excess energy intake, insulin resistance and altered lipid metabolism can change the concentrations and movement of glucose, fatty acids, triglycerides, ketone bodies, amino acids and other metabolites. These changes can influence insulin signalling, inflammation, oxidative stress, hormonal signalling, mitochondrial function and gene regulation.
Patient history, lifestyle assessment, blood tests, urine analysis, hormonal assessment, metabolic biomarkers, body composition and advanced molecular testing where clinically indicated. Specialised metabolomic, genomic or transcriptomic investigations may provide additional biological information.
Identify → Correct → Measure. Personalised programmes may target nutrition, carbohydrate and energy metabolism, insulin sensitivity, body composition, physical activity, sleep, stress, nutritional deficiencies, and hormonal or medical factors.
Cancer cells frequently undergo profound metabolic reprogramming. They may alter the way they utilise glucose, amino acids, lipids and other nutrients to support energy production, growth, survival and proliferation.
These changes can create distinctive metabolic environments within and around a tumour. Altered metabolism can also influence signalling and gene regulation.
Cancer-associated metabolic pathways can alter glucose metabolites, lactate, amino acids, lipids, TCA-cycle metabolites and redox molecules. These can influence the tumour microenvironment, immune responses, epigenetic regulation and cellular signalling.
Depending on the cancer and clinical indication, assessment may integrate medical and treatment history, pathology, imaging, standard blood tests, metabolic markers, molecular profiling, genomics/NGS, transcriptomics and specialised metabolomics where appropriate.
Our metabolic approach is designed to complement—not replace—evidence-based oncology care. We focus on metabolic health, nutrition, body composition, physical function and other modifiable factors before, during and after cancer treatment, coordinated with the oncology team where appropriate.
The kidneys regulate far more than urine production. They help maintain fluid balance, electrolytes, acid-base balance, blood pressure, mineral metabolism, hormonal signalling and removal of metabolic waste.
When kidney function declines, the body’s internal metabolic environment changes.
With declining kidney function, urea and other uraemic solutes may accumulate, while electrolyte, mineral and acid-base disturbances may develop. Diabetes, insulin resistance, hypertension, obesity and dyslipidaemia can also contribute to kidney damage and CKD progression.
Kidney function, eGFR, creatinine, urine albumin/protein, electrolytes, acid-base status, glucose and insulin metabolism, blood pressure, lipids, nutrition, medication review and relevant imaging may be assessed.
The priority is kidney protection and slowing disease progression while addressing modifiable metabolic drivers: blood pressure optimisation, diabetes management, appropriate nutrition, sodium management, protein individualisation, weight and metabolic health, medication optimisation and cardiovascular risk reduction.
Every cell carries DNA, but different cells use different combinations of genes. That pattern of gene activity helps determine cellular identity and function.
Modern biology has demonstrated that cellular states can, under specific laboratory conditions, be experimentally reprogrammed by changing regulatory networks and gene-expression patterns.
Gene expression and metabolism are deeply interconnected. Metabolic pathways generate molecules involved in energy production, cellular signalling, DNA and histone modification, redox balance and protein function.
Mitochondria sit at the centre of cellular energy metabolism. Changes in mitochondrial function can affect ATP production, reactive oxygen species, metabolic signalling, cellular stress responses and cell survival.
Our Cellular Reprogramming programme focuses on the assessment and research of cellular, metabolic and mitochondrial health. Where appropriate, this may involve metabolic assessment, molecular biomarkers, mitochondrial health indicators, genomics, transcriptomics, epigenetic assessment and metabolomics.
Ageing is accompanied by changes across multiple biological systems, including metabolism, mitochondrial function, body composition, insulin sensitivity, inflammation, cardiovascular fitness, muscle mass, cellular signalling and epigenetic patterns.
At Classia Health, longevity is approached as a whole-system health programme, not simply an anti-ageing treatment.
Insulin resistance may increase, muscle mass may decline, visceral fat may accumulate, mitochondrial function may change and chronic low-grade inflammation may rise. Together, these changes can increase the risk of diabetes, cardiovascular disease, frailty, fatty liver, cognitive decline and loss of physical independence.
Metabolic health, body composition, muscle strength, cardiovascular fitness, VO₂ max, blood pressure, glucose and insulin, lipids, inflammatory markers, nutritional status, sleep and lifestyle. Where appropriate, epigenetic age, genomics and metabolomics may also be considered.
We focus on nutrition, exercise, muscle preservation, cardiovascular fitness, sleep, weight and body composition, metabolic health, nutritional optimisation and appropriate medical risk management—and then measure progress.
Ageing can bring interconnected challenges such as muscle loss, reduced mobility, poor appetite, metabolic disease, multiple medicines, frailty, falls, cognitive changes and social isolation.
At Classia Health, senior care combines metabolic health with functional health and supportive care.
Older adults can experience significant changes in glucose metabolism, protein metabolism, muscle mass, hydration, electrolytes, hormones, nutrient absorption and mitochondrial function. Sarcopenia—the progressive loss of muscle mass and strength—is particularly important.
Medical history, medication review, metabolic markers, nutrition, body composition, muscle strength, walking ability, balance, functional capacity, cognitive and emotional wellbeing, and social support.
Nutrition, appropriate protein intake, strength and mobility, fall prevention, metabolic health, medication review, hydration, social engagement, functional rehabilitation and assisted care, supported through Day Care, Assisted Care and Senior Health programmes.
Planned, supervised care for clinically stable patients who do not require continuous hospital admission.
Many cancer and CKD patients can receive selected planned services in a day-care setting when they are clinically stable and the treating specialist determines that hospital admission is not required.
Our goal is to provide a calm, coordinated setting for scheduled treatment, monitoring, supportive care and recovery.
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Metabolomics • Gene Expression • Cellular Health
Understand the Biology. Identify the Drivers. Intervene Precisely. Measure the Change.
Classia Health
No.58, 2nd Cross, Chowdiah Block,
R.T Nagar, Bangalore - 560032, Karnataka.